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August 13, 2018

Digital Biomarkers for Cognitive Disorders

Commentary
Julie Carty
&

In a data-rich world, digital biomarkers have the potential to reduce costs, and improve patient outcomes. But what is a digital biomarker? Today we decided to take a look at the third and final topic that will feature in the HealthXL Global Gathering on February 22-23 in Basel Switzerland, Digital Biomarkers for Cognitive Disorders. We took a look at some of the innovations and companies that are developing the solutions of tomorrow, but first, what is a biomarker?

What is a Biomarker?

Simply put a biomarker is a measurable indicator of the severity or presence of some disease state. Thus, a digital biomarker is a measurable indicator of some disease state that is determined using a connected digital device. We decided to take a closer look at some of the companies and innovations in the space. Check it out below!

Why are we talking about it?

Cognitive disorders, often not well understood, are a disease category that has the potential to be impacted by digital biomarkers. Take for example a person with diagnosed with Parkinson’s Disease, they develop the disease from a complex interaction between their genotype and environment which leads to the parkinson’s phenotype: Tremor, Bradykinesia, postural instability. The beauty of digital biomarkers comes from when they can be deployed to objectively detect these phenotypes which can usually only be detected subjectively by a doctor later on in the progression of the disease. Check out three companies that we have found that are making strides within this nascent space:

Companies to watch that are innovating in the space

Neurotrack

Neurotrack’s first product, Imprint, released early this year, is a digital cognitive test that enables earlier and more effective evaluation of patients who may be at risk for cognitive decline. Imprint is a 5-minute web-based test that uses eye-tracking technology to assess brain function. Neurotrack has raised $8 million in funding to date and recently partnered with Welkin Health for a Study on Advanced Solutions for Individuals At Risk for Cognitive Decline.

Akilii

Akili is building a clinically validated, cognitive therapeutic assessment and diagnostic tool that looks and feels like a video game. Akili’s leading project, EVO is currently being evaluated in the STARS-ADHD study. They have raised $73 million in funding to date.

NeuraMetrix

Neurametrix detects and monitors brain diseases, disorders, and injuries with non-invasive software that measures sub-clinical human cognitive and motor function based on typing cadence. The solution is so sensitive it notices inconsistencies in typing cadence that would usually go unnoticed by the naked eye.

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We can provide an introduction on your behalf so that you can contact them directly with any questions/queries on this topic. Simply click on the link below to request an introduction.

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We can provide an introduction on your behalf so that you can contact them directly with any questions/queries on this topic. Simply click on the link below to request an introduction.

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Caleb Bank
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Jim O'Donoghue
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President , S3 Connected Health
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Eugene Borukhovich
Eugene Borukhovich
Chairman and COO of YourCoach.Health
Jim O'Donoghue
Jim O'Donoghue
President , S3 Connected Health
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Head of R&D Digital, Almirall
George Platings
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Market Development Specialist at uMotif

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DTx- Employer Partnerships

5th August @ 9:45AM EDT

Join our Digital Health Meeting as discuss employer partnerships for DTx companies. Apply now to hear valuable insights from thought leaders in the industry and connect with new people.

Featuring
Eugene Borukhovich
Eugene Borukhovich
Chairman and COO of YourCoach.Health
Caleb Bank
Caleb Bank
Product Marketing at NuvoAir
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Eugene Borukhovich
Eugene Borukhovich
Chairman and COO of YourCoach.Health
Caleb Bank
Caleb Bank
Product Marketing at NuvoAir
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)

Masterclass: Reimbursement models for DTx in the US

10th August @ 10:45AM EDT

Join us in this US-focused interactive masterclass led by Happify Health where we will discuss the best reimbursement models for DTx. Apply now to gain valuable insights from thought leaders in the industry.

Featuring
Chris Wasden
Chris Wasden
Head of HappifyDTx, Happify Health
Featuring
Chris Wasden
Chris Wasden
Head of HappifyDTx, Happify Health
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)

DTx opportunity for pharmaceutical companies

11th August @ 9:45AM EDT

Join this informal conversation with other thought leaders to discuss the current and future opportunities for pharma in DTx. Great opportunity to connect with peers and meet new people in this space.

Featuring
Eugene Borukhovich
Eugene Borukhovich
Chairman and COO of YourCoach.Health
Jim O'Donoghue
Jim O'Donoghue
President , S3 Connected Health
Featuring
Eugene Borukhovich
Eugene Borukhovich
Chairman and COO of YourCoach.Health
Jim O'Donoghue
Jim O'Donoghue
President , S3 Connected Health

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