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January 16, 2020

HealthXL Report: Clinical Trials Optimization with Digital Health

Commentary
Chandana Fitzgerald
&

We started our conversations on the digital opportunity for clinical trials at the HealthXL Global Gathering in September 2019. And after many months of exchanges, debates and conversation, our long awaited report on Clinical Trial Optimization is finally here! 

Why is this important? Some stats and facts. 

The People 

Our Q1 report is completely expert led, oozing with opinions from the catalysts of the industry including: 

Clincial Trials Report Contirbutors
Report Contributors

Key Takeaways 

What is the real future for digital in clinical trials? Has digital made clinical trials cheaper and faster? Has regulation changed to support these ‘new age’ trials? Do we understand what digital signals correspond to clinical end points? These questions have inspired this HealthXL report on Clinical Trial Optimization. We explore the hype vs reality of this opportunity under 5 key themes that were handpicked by HealthXL members. Below we summarize our key takeaways: 


Can Digital Strategies improve Clinical Trial Recruitment and Retention? 

Digital is helping pharma reach new cohorts of patients where they share their stories: online. It is also enabling pharma to co-create new strategies with healthcare providers that allow patients to partake in trials from their homes. However, it is too early to prove that a full online-only engagement modality will dramatically increase patient enrollment into clinical trials or retain patients in clinical trials. We also want to steer away from the use of the word ‘siteless’ trial and promote the use of ‘decentralized’ or ‘virtual’ trial. 


Can Digital Health Lower Costs of Clinical Trials? 

We believe technology will enable ‘cost shifting’ rather than gross cost reduction, by helping to better manage the cost of routine tasks and logistics. This may lead to new business models or additional profits based on expanded data collection. Short term cost escalation will yield longer term benefits.

Will Digital Health Expand Clinical Endpoints for Clinical Trials? 

Even if we lack best practices at this moment in time, digital biomarkers allow for continuous collection of real-world patient data in clinical trials. We are attempting to understand what digital biomarkers are, and which ones can be captured for various indications, and through what devices. 

Who is Driving the Changes to Regulation Necessary to Adopt Digital Tools in Clinical Trials? 

We believe that pharma, consortia of pharma (e.g. Neuroscience Consortium) and digital health innovators will lead the way through R&D and piloting. 

What Areas are Ripe for Optimization with Digital Health? 

Much hope has been placed on the utilization of digital health technologies to manage and treat chronic conditions. Cardiometabolic conditions are regarded as one area ripe for disruption due to the high burden as well as large populations impacted along with many devices aimed at that sector currently. Pharma is increasingly interested in how similar offerings could be expanded towards more high risk and rare conditions in neurology and oncology.

Therapy areas: Cardiology, Oncology, and Neurology

Clinical Trial Pathway: Recruitment, Retention, Logistics 


Grounded in Data and Evidence

We’ve identified 119 (and counting) start-ups working to optimize clinical trials along the pathway (protocol design and review, patient recruitment, site selection, patient engagement, data collection, as well as operational management and risk monitoring) to help reach the promise of faster, cheaper, better. We have also picked out ongoing studies, pilots and initiatives already in play to make tech enabled trial optimization a reality. 

Sample clinical studies that are currently collecting and measuring digital endpoints
Users can explore all company data at:  https://portal-beta.healthxl.com/  Not yet a HealthXL Platform user? Request Access here:   https://portal-beta.healthxl.com/request-access 


Next Steps: Our Future Expectations 


Do you have experience leveraging digital solutions to improve clinical trials? Are you a PI looking to identify an appropriate digital solution to help you overcome an investigation challenge? Do you agree/disagree with our findings?We’d love to hear from you, and of your initiatives in translating hype to pragmatic reality. 

We can provide an introduction on your behalf so that you can contact them directly with any questions/queries on this topic. Simply click on the link below to request an introduction.

We can provide an introduction on your behalf so that you can contact them directly with any questions/queries on this topic. Simply click on the link below to request an introduction.

Request an Introduction

We can provide an introduction on your behalf so that you can contact them directly with any questions/queries on this topic. Simply click on the link below to request an introduction.

Request an Introduction

Ready to read more? HealthXL members can access the full peak of the report on the HealthXL Community Hub.

Not yet a member of HealthXL? Download your 11 page snapshot of the report.

Download your 11 page snapshot

Connect with peers and share insights

Don't miss out on the discussion of the latest insights and reports on digital health. Meet with peers and take a deep dive for 75 minutes. Unlike at webinars, you can freely exchange experiences and insights to solve challenges and design the future of DTx.

Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)

DTx- Employer Partnerships

5th August @ 9:45AM EDT

Join our Digital Health Meeting as discuss employer partnerships for DTx companies. Apply now to hear valuable insights from thought leaders in the industry and connect with new people.

Featuring
Eugene Borukhovich
Eugene Borukhovich
Chairman and COO of YourCoach.Health
Caleb Bank
Caleb Bank
Product Marketing at NuvoAir
Featuring
Eugene Borukhovich
Eugene Borukhovich
Chairman and COO of YourCoach.Health
Caleb Bank
Caleb Bank
Product Marketing at NuvoAir
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)

Masterclass: Reimbursement models for DTx in the US

10th August @ 10:45AM EDT

Join us in this US-focused interactive masterclass led by Happify Health where we will discuss the best reimbursement models for DTx. Apply now to gain valuable insights from thought leaders in the industry.

Featuring
Chris Wasden
Chris Wasden
Head of HappifyDTx, Happify Health
Featuring
Chris Wasden
Chris Wasden
Head of HappifyDTx, Happify Health
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)

DTx opportunity for pharmaceutical companies

11th August @ 9:45AM EDT

Join this informal conversation with other thought leaders to discuss the current and future opportunities for pharma in DTx. Great opportunity to connect with peers and meet new people in this space.

Featuring
Eugene Borukhovich
Eugene Borukhovich
Chairman and COO of YourCoach.Health
Jim O'Donoghue
Jim O'Donoghue
President , S3 Connected Health
Featuring
Eugene Borukhovich
Eugene Borukhovich
Chairman and COO of YourCoach.Health
Jim O'Donoghue
Jim O'Donoghue
President , S3 Connected Health
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)

The future of companion DTx

17th August @ 10:45AM EDT

Join us as we discuss the future of companion DTx products. This 75 minute session is guaranteed to be filled with interesting debate and great conversation so apply now to secure your place.

Featuring
Céline Ulmann
Céline Ulmann
Head of R&D Digital, Almirall
George Platings
George Platings
Market Development Specialist at uMotif
Featuring
Céline Ulmann
Céline Ulmann
Head of R&D Digital, Almirall
George Platings
George Platings
Market Development Specialist at uMotif

Are you a HealthXL Member? See the Full Report Here

Non-HealthXL Member? You can purchase the report HERE

HealthXL Digital Health Meetings

Want to join the discussion now?

Join our Digital Health Meetings and take a deep dive for 75 minutes into topics like digital therapeutics, patient support, telehealth, clinical trials, dermatology and many more. These Meetings are not regular webinars: No audience, no recording and no hiding behind a screen. You actively participate in a discussion to solve your present challenges and design the future of digital health. And with a free account on our Community Hub, you stay connected and up-to-date on the latest news and insights, allowing you to fully immerse yourself in the topic before, during and after.

Telemedicine & Virtual Care Delivery
Telemedicine & Virtual Care Delivery
Telemedicine & Virtual Care Delivery
Telemedicine & Virtual Care Delivery

Virtual Care for Diabetes: Commercialization models

4th August @ 10:45AM EDT

Join us as we discuss what are the most scalable and sustainable commercialization models for Virtual Care companies in the diabetes space. Apply now to get involved in the conversation, network with peers and share your thoughts on the topic.

Featuring
Jim Howard
Jim Howard
CEO, Readout Health
Michael Freni
Michael Freni
Director, Business Development, Partners Innovation at Partners HealthCare
Featuring
Jim Howard
Jim Howard
CEO, Readout Health
Michael Freni
Michael Freni
Director, Business Development, Partners Innovation at Partners HealthCare
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)

DTx- Employer Partnerships

5th August @ 9:45AM EDT

Join our Digital Health Meeting as discuss employer partnerships for DTx companies. Apply now to hear valuable insights from thought leaders in the industry and connect with new people.

Featuring
Eugene Borukhovich
Eugene Borukhovich
Chairman and COO of YourCoach.Health
Caleb Bank
Caleb Bank
Product Marketing at NuvoAir
Featuring
Eugene Borukhovich
Eugene Borukhovich
Chairman and COO of YourCoach.Health
Caleb Bank
Caleb Bank
Product Marketing at NuvoAir
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)

Masterclass: Reimbursement models for DTx in the US

10th August @ 10:45AM EDT

Join us in this US-focused interactive masterclass led by Happify Health where we will discuss the best reimbursement models for DTx. Apply now to gain valuable insights from thought leaders in the industry.

Featuring
Chris Wasden
Chris Wasden
Head of HappifyDTx, Happify Health
Featuring
Chris Wasden
Chris Wasden
Head of HappifyDTx, Happify Health
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)
Digital Therapeutics (DTX)

DTx opportunity for pharmaceutical companies

11th August @ 9:45AM EDT

Join this informal conversation with other thought leaders to discuss the current and future opportunities for pharma in DTx. Great opportunity to connect with peers and meet new people in this space.

Featuring
Eugene Borukhovich
Eugene Borukhovich
Chairman and COO of YourCoach.Health
Jim O'Donoghue
Jim O'Donoghue
President , S3 Connected Health
Featuring
Eugene Borukhovich
Eugene Borukhovich
Chairman and COO of YourCoach.Health
Jim O'Donoghue
Jim O'Donoghue
President , S3 Connected Health

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